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Bulge oligonucleotide as an inhibitory agent of bacterial topoisomerase I

Bacterial topoisomerase I (Btopo I) was defined as potential target for discovery of new antibacterial compounds. Various oligonucleotides containing bulge structure were designed and synthesised as inhibitors to Btopo I in this investigation. The results of this study demonstrated that the designed...

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Podrobná bibliografie
Vydáno v:J Enzyme Inhib Med Chem
Hlavní autoři: Yang, Zhaoqi, Jiang, Tuoyu, Zhong, Hanshi, Kang, Yu
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009931/
https://ncbi.nlm.nih.gov/pubmed/29281935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1419218
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