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Bulge oligonucleotide as an inhibitory agent of bacterial topoisomerase I
Bacterial topoisomerase I (Btopo I) was defined as potential target for discovery of new antibacterial compounds. Various oligonucleotides containing bulge structure were designed and synthesised as inhibitors to Btopo I in this investigation. The results of this study demonstrated that the designed...
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| Publicat a: | J Enzyme Inhib Med Chem |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6009931/ https://ncbi.nlm.nih.gov/pubmed/29281935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1419218 |
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