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ZFAT binds to centromeres to control noncoding RNA transcription through the KAT2B–H4K8ac–BRD4 axis

Centromeres are genomic regions essential for faithful chromosome segregation. Transcription of noncoding RNA (ncRNA) at centromeres is important for their formation and functions. Here, we report the molecular mechanism by which the transcriptional regulator ZFAT controls the centromeric ncRNA tran...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Ishikura, Shuhei, Nakabayashi, Kazuhiko, Nagai, Masayoshi, Tsunoda, Toshiyuki, Shirasawa, Senji
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641738/
https://ncbi.nlm.nih.gov/pubmed/32997115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa815
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