The Nuclear Zinc Finger Protein Zfat Maintains FoxO1 Protein Levels in Peripheral T Cells by Regulating the Activities of Autophagy and the Akt Signaling Pathway

Forkhead box O1 (FoxO1) is a key molecule for the development and functions of peripheral T cells. However, the precise mechanisms regulating FoxO1 expression in peripheral T cells remain elusive. We previously reported that Zfat(f/f)-CD4Cre mice showed a marked decline in FoxO1 protein levels in pe...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ishikura, Shuhei, Iwaihara, Yuri, Tanaka, Yoko, Luo, Hao, Nishi, Kensuke, Doi, Keiko, Koyanagi, Midori, Okamura, Tadashi, Tsunoda, Toshiyuki, Shirasawa, Senji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946940/
https://ncbi.nlm.nih.gov/pubmed/27226588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.723734
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