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Small-molecule sensitization of RecBCD helicase–nuclease to a Chi hotspot-activated state
Coordinating multiple activities of complex enzymes is critical for life, including transcribing, replicating and repairing DNA. Bacterial RecBCD helicase–nuclease must coordinate DNA unwinding and cutting to repair broken DNA. Starting at a DNA end, RecBCD unwinds DNA with its fast RecD helicase on...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7641324/ https://ncbi.nlm.nih.gov/pubmed/32597964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa534 |
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