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RecBCD Enzyme “Chi Recognition” Mutants Recognize Chi Recombination Hotspots in the Right DNA Context

RecBCD enzyme is a complex, three-subunit protein machine essential for the major pathway of DNA double-strand break repair and homologous recombination in Escherichia coli. Upon encountering a Chi recombination-hotspot during DNA unwinding, RecBCD nicks DNA to produce a single-stranded DNA end onto...

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Foilsithe in:Genetics
Main Authors: Amundsen, Susan K., Sharp, Jake W., Smith, Gerald R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Genetics Society of America 2016
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012381/
https://ncbi.nlm.nih.gov/pubmed/27401752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.191056
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