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Chi Hotspot Activity in Escherichia coli Without RecBCD Exonuclease Activity: Implications for the Mechanism of Recombination

The major pathway of genetic recombination and DNA break repair in Escherichia coli requires RecBCD enzyme, a complex nuclease and DNA helicase regulated by Chi sites (5′-GCTGGTGG-3′). During its unwinding of DNA containing Chi, purified RecBCD enzyme has two alternative nucleolytic reactions, depen...

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Bibliografiska uppgifter
Huvudupphovsmän: Amundsen, Susan K., Smith, Gerald R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Copyright © 2007 by the Genetics Society of America 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774988/
https://ncbi.nlm.nih.gov/pubmed/17110484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.065524
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