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The RecB helicase-nuclease tether mediates Chi hotspot control of RecBCD enzyme

In bacteria, repair of DNA double-strand breaks uses a highly conserved helicase–nuclease complex to unwind DNA from a broken end and cut it at specific DNA sequences called Chi. In Escherichia coli the RecBCD enzyme also loads the DNA strand-exchange protein RecA onto the newly formed end, resultin...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Amundsen, Susan K, Smith, Gerald R
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326792/
https://ncbi.nlm.nih.gov/pubmed/30445486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1132
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