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qDRIP: a method to quantitatively assess RNA–DNA hybrid formation genome-wide

R-loops are dynamic, co-transcriptional nucleic acid structures that facilitate physiological processes but can also cause DNA damage in certain contexts. Perturbations of transcription or R-loop resolution are expected to change their genomic distribution. Next-generation sequencing approaches to m...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Crossley, Magdalena P, Bocek, Michael J, Hamperl, Stephan, Swigut, Tomek, Cimprich, Karlene A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641308/
https://ncbi.nlm.nih.gov/pubmed/32544226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa500
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