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The contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability
Accurate DNA replication and DNA repair are crucial for the maintenance of genome stability, and it is generally accepted that failure of these processes is a major source of DNA damage in cells. Intriguingly, recent evidence suggests that DNA damage is more likely to occur at genomic loci with high...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4051866/ https://ncbi.nlm.nih.gov/pubmed/24746923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.03.023 |
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