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R-loops as cellular regulators and genomic threats
During transcription, the nascent RNA strand can base pair with its template DNA, displacing the non-template strand as ssDNA and forming a structure called an R-loop. R-loops are common across many domains of life and cause DNA damage in certain contexts. In this review, we summarize recent results...
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| Pubblicato in: | Mol Cell |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6402819/ https://ncbi.nlm.nih.gov/pubmed/30735654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.01.024 |
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