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Differential abundance testing on single-cell data using K-nearest neighbour graphs

Current computational workflows for comparative analyses of single cell datasets typically use discrete clusters as input when testing for differential abundance between experimental conditions. However, clusters do not always provide the appropriate resolution and cannot capture continuous trajecto...

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Detalles Bibliográficos
Publicado en:Nat Biotechnol
Main Authors: Dann, Emma, Henderson, Neil C., Teichmann, Sarah A., Morgan, Michael D., Marioni, John C.
Formato: Artigo
Idioma:Inglês
Publicado: 2022
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7617075/
https://ncbi.nlm.nih.gov/pubmed/34594043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-021-01033-z
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