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Differential abundance testing on single-cell data using K-nearest neighbour graphs

Current computational workflows for comparative analyses of single cell datasets typically use discrete clusters as input when testing for differential abundance between experimental conditions. However, clusters do not always provide the appropriate resolution and cannot capture continuous trajecto...

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Podrobná bibliografie
Vydáno v:Nat Biotechnol
Hlavní autoři: Dann, Emma, Henderson, Neil C., Teichmann, Sarah A., Morgan, Michael D., Marioni, John C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2022
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7617075/
https://ncbi.nlm.nih.gov/pubmed/34594043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-021-01033-z
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