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Differential abundance testing on single-cell data using K-nearest neighbour graphs

Current computational workflows for comparative analyses of single cell datasets typically use discrete clusters as input when testing for differential abundance between experimental conditions. However, clusters do not always provide the appropriate resolution and cannot capture continuous trajecto...

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Publicat a:Nat Biotechnol
Autors principals: Dann, Emma, Henderson, Neil C., Teichmann, Sarah A., Morgan, Michael D., Marioni, John C.
Format: Artigo
Idioma:Inglês
Publicat: 2022
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7617075/
https://ncbi.nlm.nih.gov/pubmed/34594043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-021-01033-z
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