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Differential abundance testing on single-cell data using K-nearest neighbour graphs

Current computational workflows for comparative analyses of single cell datasets typically use discrete clusters as input when testing for differential abundance between experimental conditions. However, clusters do not always provide the appropriate resolution and cannot capture continuous trajecto...

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Bibliografske podrobnosti
izdano v:Nat Biotechnol
Main Authors: Dann, Emma, Henderson, Neil C., Teichmann, Sarah A., Morgan, Michael D., Marioni, John C.
Format: Artigo
Jezik:Inglês
Izdano: 2022
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7617075/
https://ncbi.nlm.nih.gov/pubmed/34594043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-021-01033-z
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