Hepatitis C virus RNA is 5’ capped with flavin adenine dinucleotide (FAD)

RNA viruses have evolved elaborate strategies for protection of their genomes, including 5’ capping. However, so far no RNA 5’ cap was identified for hepatitis C virus (HCV) (1,2), which causes chronic infection, liver cirrhosis and cancer(3). Here, we demonstrate that the cellular metabolite flavin...

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Bibliografski detalji
Izdano u:Nature
Glavni autori: Sherwood, Anna V., Rivera-Rangel, Lizandro R., Ryberg, Line A., Larsen, Helena S., Anker, Klara M., Costa, Rui, Vågbø, Cathrine B., Jakljevič, Eva, Pham, Long V., Fernandez-Antunez, Carlota, Indrisiunaite, Gabriele, Podolska-Charlery, Agnieszka, Grothen, Julius E.R., Langvad, Nicklas W., Fossat, Nicolas, Offersgaard, Anna, Al-Chaer, Amal, Nielsen, Louise, Kuśnierczyk, Anna, Sølund, Christina, Weis, Nina, Gottwein, Judith M., Holmbeck, Kenn, Bottaro, Sandro, Ramirez, Santseharay, Bukh, Jens, Scheel, Troels K.H., Vinther, Jeppe
Format: Artigo
Jezik:Inglês
Izdano: 2023
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616780/
https://ncbi.nlm.nih.gov/pubmed/37407817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-023-06301-3
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