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Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains

Hepatitis C virus (HCV) infection is a leading cause of chronic liver diseases worldwide, but treatment options are limited. Basic HCV research required for vaccine and drug development has been hampered by inability to culture patient isolates, and to date only the JFH1 (genotype 2a) recombinant re...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Li, Yi-Ping, Ramirez, Santseharay, Gottwein, Judith M., Scheel, Troels K. H., Mikkelsen, Lotte, Purcell, Robert H., Bukh, Jens
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344947/
https://ncbi.nlm.nih.gov/pubmed/22467829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203829109
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