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When should factorial designs be used for late-phase randomised controlled trials?

BACKGROUND: A 2×2 factorial design evaluates two interventions (A versus control and B versus control) by randomising to control, A-only, B-only or both A and B together. Extended factorial designs are also possible (e.g. 3×3 or 2×2×2). Factorial designs often require fewer resources and participant...

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Dades bibliogràfiques
Publicat a:Clin Trials
Autors principals: White, Ian R, Szubert, Alexander J, Choodari-Oskooei, Babak, Walker, A Sarah, Parmar, Mahesh KB
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2023
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615816/
https://ncbi.nlm.nih.gov/pubmed/37904490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/17407745231206261
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