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RHO GTPases in cancer: known facts, open questions, and therapeutic challenges
RHO GTPases have been traditionally associated with protumorigenic functions. While this paradigm is still valid in many cases, recent data have unexpectedly revealed that RHO proteins can also play tumor suppressor roles. RHO signaling elements can also promote both pro- and antitumorigenic effects...
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| Publicado no: | Biochem Soc Trans |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7615761/ https://ncbi.nlm.nih.gov/pubmed/29871878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20170531 |
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