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RHO GTPases in cancer: known facts, open questions, and therapeutic challenges

RHO GTPases have been traditionally associated with protumorigenic functions. While this paradigm is still valid in many cases, recent data have unexpectedly revealed that RHO proteins can also play tumor suppressor roles. RHO signaling elements can also promote both pro- and antitumorigenic effects...

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Podrobná bibliografie
Vydáno v:Biochem Soc Trans
Hlavní autor: Bustelo, Xosé R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615761/
https://ncbi.nlm.nih.gov/pubmed/29871878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20170531
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