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RHO GTPases in cancer: known facts, open questions, and therapeutic challenges
RHO GTPases have been traditionally associated with protumorigenic functions. While this paradigm is still valid in many cases, recent data have unexpectedly revealed that RHO proteins can also play tumor suppressor roles. RHO signaling elements can also promote both pro- and antitumorigenic effects...
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| Veröffentlicht in: | Biochem Soc Trans |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7615761/ https://ncbi.nlm.nih.gov/pubmed/29871878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20170531 |
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