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Rho GTPases as therapeutic targets in cancer (Review)

Rho GTPases are key molecular switches controlling the transduction of external signals to cytoplasmic and nuclear effectors. In the last few years, the development of genetic and pharmacological tools has allowed a more precise definition of the specific roles of Rho GTPases in cancer. The aim of t...

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Bibliographic Details
Published in:Int J Oncol
Main Authors: Cardama, G.A., Gonzalez, N., Maggio, J., Menna, P. Lorenzano, Gomez, D.E.
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592879/
https://ncbi.nlm.nih.gov/pubmed/28848995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2017.4093
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