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RAS GTPase-dependent pathways in developmental diseases: old guys, new lads, and current challenges

Deregulated RAS signaling is associated with increasing numbers of congenital diseases usually referred to as RASopathies. The spectrum of genes and mutant alleles causing these diseases has been significantly expanded in recent years. This progress has triggered new challenges, including the origin...

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Bibliografiske detaljer
Udgivet i:Curr Opin Cell Biol
Main Authors: Bustelo, Xosé R, Crespo, Piero, Fernández-Pisonero, Isabel, Rodríguez-Fdez, Sonia
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615762/
https://ncbi.nlm.nih.gov/pubmed/30007125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2018.06.007
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