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Rho guanosine nucleotide exchange factors are not such bad guys after all in cancer(a)
Rho GDP/GTP exchange factors (GEFs), the enzymes that trigger the stimulation of Rho GTPases during cell signaling, are widely deemed as potential therapeutic targets owing to their protumorigenic functions. However, the sparse use of animal models has precluded a full understanding of their pathoph...
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| Publié dans: | Small GTPases |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7549630/ https://ncbi.nlm.nih.gov/pubmed/29313423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2018.1423851 |
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