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Rho guanosine nucleotide exchange factors are not such bad guys after all in cancer(a)
Rho GDP/GTP exchange factors (GEFs), the enzymes that trigger the stimulation of Rho GTPases during cell signaling, are widely deemed as potential therapeutic targets owing to their protumorigenic functions. However, the sparse use of animal models has precluded a full understanding of their pathoph...
Gardado en:
| Publicado en: | Small GTPases |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7549630/ https://ncbi.nlm.nih.gov/pubmed/29313423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2018.1423851 |
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