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Drug Vulnerabilities and Disease Prognosis Linked to the Stem Cell-Like Gene Expression Program Triggered by the RHO GTPase Activator VAV2 in Hyperplastic Keratinocytes and Head and Neck Cancer

SIMPLE SUMMARY: Head and neck squamous cell carcinoma are epithelial tumors with a very poor prognosis. They are also in high need of new targeted and immune-based therapeutics to limit tumor recurrence and improve long-term survival. The poor prognosis of patients with head and neck tumors is usual...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Lorenzo-Martín, Luis Francisco, Menacho-Márquez, Mauricio, Bustelo, Xosé R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563609/
https://ncbi.nlm.nih.gov/pubmed/32899210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092498
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