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ASPP2 binds to hepatitis C virus NS5A protein via an SH3 domain/PxxP motif-mediated interaction and potentiates infection

Hepatitis C virus (HCV) infects millions of people worldwide and is a leading cause of liver disease. Despite recent advances in antiviral therapies, viral resistance can limit drug efficacy and understanding the mechanisms that confer viral escape is important. We employ an unbiased interactome ana...

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Detaylı Bibliyografya
Yayımlandı:J Gen Virol
Asıl Yazarlar: Smirnov, Artem, Magri, Andrea, Lotz, Rebecca, Han, Xiaoyue, Yin, Chunhong, Harris, Mark, Osterburg, Christian, Dötsch, Volker, McKeating, Jane A., Lu, Xin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2023
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615710/
https://ncbi.nlm.nih.gov/pubmed/37750869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001895
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