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Replacement of the Hepatitis E Virus ORF3 Protein PxxP Motif with Heterologous Late Domain Motifs Affects Virus Release Via Interaction with TSG101

The ORF3 protein of hepatitis E virus (HEV) contains a “PSAP” amino acid late domain motif, which allows for interaction with the endosomal sorting complexes required for transport (ESCRT) pathway aiding virion release. Late domain motifs are interchangeable with other viral late domain motifs in se...

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Bibliografische gegevens
Gepubliceerd in:Virology
Hoofdauteurs: Kenney, Scott P., Wentworth, Jacquelyn, Heffron, Connie L., Meng, Xiang-Jin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679584/
https://ncbi.nlm.nih.gov/pubmed/26457367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.09.012
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