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Replacement of the Hepatitis E Virus ORF3 Protein PxxP Motif with Heterologous Late Domain Motifs Affects Virus Release Via Interaction with TSG101

The ORF3 protein of hepatitis E virus (HEV) contains a “PSAP” amino acid late domain motif, which allows for interaction with the endosomal sorting complexes required for transport (ESCRT) pathway aiding virion release. Late domain motifs are interchangeable with other viral late domain motifs in se...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Kenney, Scott P., Wentworth, Jacquelyn, Heffron, Connie L., Meng, Xiang-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679584/
https://ncbi.nlm.nih.gov/pubmed/26457367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.09.012
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