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Domain III of NS5A contributes to both RNA replication and assembly of hepatitis C virus particles

The hepatitis C virus (HCV) NS5A protein plays a critical role in viral RNA replication and has recently been shown to play a role in particle production in the infectious genotype 2a HCV clone (JFH-1). Here, we show that alanine substitutions of serines 2428/2430 within the C-terminal domain III of...

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Bibliografiske detaljer
Udgivet i:J Gen Virol
Main Authors: Hughes, Mair, Griffin, Stephen, Harris, Mark
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615708/
https://ncbi.nlm.nih.gov/pubmed/19264615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.009332-0
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