Vaccination with Plasmodium vivax Duffy-binding protein inhibits parasite growth during controlled human malaria infection

There are no licensed vaccines against Plasmodium vivax. We conducted two Phase I/IIa clinical trials to assess two vaccines targeting P. vivax Duffy-binding protein region II (PvDBPII). Recombinant viral vaccines using chimpanzee adenovirus 63 (ChAd63) and modified vaccinia virus Ankara (MVA) vecto...

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Bibliografiska uppgifter
I publikationen:Sci Transl Med
Huvudupphovsmän: Hou, Mimi M., Barrett, Jordan R., Themistocleous, Yrene, Rawlinson, Thomas A., Diouf, Ababacar, Martinez, Francisco J., Nielsen, Carolyn M., Lias, Amelia M., King, Lloyd D. W., Edwards, Nick J., Greenwood, Nicola M., Kingham, Lucy, Poulton, Ian D., Khozoee, Baktash, Goh, Cyndi, Hodgson, Susanne H., Lochlainn, Dylan J. Mac, Salkeld, Jo, Guillotte-Blisnick, Micheline, Huon, Christèle, Mohring, Franziska, Reimer, Jenny M., Chauhan, Virander S., Mukherjee, Paushali, Biswas, Sumi, Taylor, Iona J., Lawrie, Alison M., Cho, Jee-Sun, Nugent, Fay L., Long, Carole A., Moon, Robert W., Miura, Kazutoyo, Silk, Sarah E., Chitnis, Chetan E., Minassian, Angela M., Draper, Simon J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2023
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615121/
https://ncbi.nlm.nih.gov/pubmed/37437014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.adf1782
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