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Targeting a Reticulocyte Binding Protein and Duffy Binding Protein to Inhibit Reticulocyte Invasion by Plasmodium vivax

Plasmodium vivax merozoite invasion is restricted to Duffy positive reticulocytes. Merozoite interaction with the Duffy antigen is mediated by the P. vivax Duffy binding protein (PvDBP). The receptor-binding domain of PvDBP maps to an N-terminal cysteine-rich region referred to as region II (PvDBPII...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Gupta, Sonal, Singh, Shailja, Popovici, Jean, Roesch, Camille, Shakri, Ahmed Rushdi, Guillotte-Blisnick, Micheline, Huon, Christèle, Menard, Didier, Chitnis, Chetan E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043553/
https://ncbi.nlm.nih.gov/pubmed/30002416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28757-4
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