Targeting a Reticulocyte Binding Protein and Duffy Binding Protein to Inhibit Reticulocyte Invasion by Plasmodium vivax

Plasmodium vivax merozoite invasion is restricted to Duffy positive reticulocytes. Merozoite interaction with the Duffy antigen is mediated by the P. vivax Duffy binding protein (PvDBP). The receptor-binding domain of PvDBP maps to an N-terminal cysteine-rich region referred to as region II (PvDBPII...

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Publicado en:Sci Rep
Main Authors: Gupta, Sonal, Singh, Shailja, Popovici, Jean, Roesch, Camille, Shakri, Ahmed Rushdi, Guillotte-Blisnick, Micheline, Huon, Christèle, Menard, Didier, Chitnis, Chetan E.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043553/
https://ncbi.nlm.nih.gov/pubmed/30002416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28757-4
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