Antibody responses to Plasmodium vivax Duffy binding and Erythrocyte binding proteins predict risk of infection and are associated with protection from clinical Malaria

BACKGROUND: The Plasmodium vivax Duffy Binding Protein (PvDBP) is a key target of naturally acquired immunity. However, region II of PvDBP, which contains the receptor-binding site, is highly polymorphic. The natural acquisition of antibodies to different variants of PvDBP region II (PvDBPII), inclu...

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Veröffentlicht in:PLoS Negl Trop Dis
Hauptverfasser: He, Wen-Qiang, Shakri, Ahmad Rushdi, Bhardwaj, Rukmini, França, Camila T., Stanisic, Danielle I., Healer, Julie, Kiniboro, Benson, Robinson, Leanne J., Guillotte-Blisnick, Micheline, Huon, Christèle, Siba, Peter, Cowman, Alan, King, Christopher L., Tham, Wai-Hong, Chitnis, Chetan E., Mueller, Ivo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400399/
https://ncbi.nlm.nih.gov/pubmed/30768655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006987
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