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Spermine-based poly(β-amino ester)s for siRNA delivery against mutated KRAS in lung cancer
Polyethylenimine (PEI) is a highly efficient cationic polymer for nucleic acid delivery, and although it is commonly used in preclinical studies, its clinical application is limited due to concerns regarding its cytotoxicity. Poly(β-amino ester)s are a new group of biodegradable and biocompatible ca...
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| Publicado en: | Mol Pharm |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2023
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7615020/ https://ncbi.nlm.nih.gov/pubmed/37578116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.3c00206 |
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