Pulmonary siRNA Delivery with Sophisticated Amphiphilic Poly(Spermine Acrylamides) for the Treatment of Lung Fibrosis

RNA interference (RNAi) is an efficient strategy to post-transcriptionally silence gene expression. While all siRNA drugs on the market target the liver, the lung offers a variety of currently undruggable targets, which can potentially be treated with RNA therapeutics. To achieve this goal, the synt...

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Detalhes bibliográficos
Publicado no:Small
Main Authors: Adams, Friederike, Zimmermann, Christoph M., Baldassi, Domizia, Pehl, Thomas M., Weingarten, Philipp, Kachel, Iris, Kränzlein, Moritz, Jürgens, David C., Braubach, Peter, Alexopoulos, Ioannis, Wygrecka, Malgorzata, Merkel, Olivia M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2024
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616748/
https://ncbi.nlm.nih.gov/pubmed/38126895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.202308775
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