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Characterisation of amyloid structures in aging C. elegans using fluorescence lifetime imaging
Amyloid fibrils are associated with a number of neurodegenerative diseases such as Huntington’s and Alzheimer’s disease. These amyloid fibrils can sequester endogenous metastable proteins as well as components of the proteostasis network (PN) and thereby exacerbate protein misfolding in the cell. Th...
Guardat en:
| Publicat a: | J Vis Exp |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614926/ https://ncbi.nlm.nih.gov/pubmed/32281971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/61004 |
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