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Characterisation of amyloid structures in aging C. elegans using fluorescence lifetime imaging
Amyloid fibrils are associated with a number of neurodegenerative diseases such as Huntington’s and Alzheimer’s disease. These amyloid fibrils can sequester endogenous metastable proteins as well as components of the proteostasis network (PN) and thereby exacerbate protein misfolding in the cell. Th...
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| Publicado no: | J Vis Exp |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614926/ https://ncbi.nlm.nih.gov/pubmed/32281971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/61004 |
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