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3′-End Processing of Eukaryotic mRNA: Machinery, Regulation, and Impact on Gene Expression

Formation of the 3′end of a eukaryotic mRNA is a key step in the production of a mature transcript. This process is mediated by a number of protein factors that cleave the pre-mRNA, add a poly(A) tail, and regulate transcription by protein dephosphorylation. Cleavage and polyadenylation specificity...

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Detalhes bibliográficos
Publicado no:Annu Rev Biochem
Main Authors: Boreikaitė, Vytautė, Passmore, Lori A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2023
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614891/
https://ncbi.nlm.nih.gov/pubmed/37001138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-052521-012445
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