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Delineating the Structural Blueprint of the Pre-mRNA 3′-End Processing Machinery
Processing of mRNA precursors (pre-mRNAs) by polyadenylation is an essential step in gene expression. Polyadenylation consists of two steps, cleavage and poly(A) synthesis, and requires multiple cis elements in the pre-mRNA and a megadalton protein complex bearing the two essential enzymatic activit...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4019069/ https://ncbi.nlm.nih.gov/pubmed/24591651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00084-14 |
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