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3′-End Processing of Eukaryotic mRNA: Machinery, Regulation, and Impact on Gene Expression
Formation of the 3′end of a eukaryotic mRNA is a key step in the production of a mature transcript. This process is mediated by a number of protein factors that cleave the pre-mRNA, add a poly(A) tail, and regulate transcription by protein dephosphorylation. Cleavage and polyadenylation specificity...
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| Udgivet i: | Annu Rev Biochem |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2023
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614891/ https://ncbi.nlm.nih.gov/pubmed/37001138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-052521-012445 |
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