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Differential nanoscale organisation of LFA-1 modulates T cell migration
Effector T-cells rely on integrins to drive adhesion and migration to facilitate their immune function. Heterodimeric transmembrane integrin LFA-1 (αLβ2) regulates adhesion and migration of effector T cells through linkage of the extracellular matrix with the intracellular actin treadmill machinery....
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| Veröffentlicht in: | J Cell Sci |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614863/ https://ncbi.nlm.nih.gov/pubmed/31471459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.232991 |
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