Restoring Tumor Immunogenicity with Dendritic Cell Reprogramming

Decreased antigen presentation contributes to the ability of cancer cells to evade the immune system. We used the minimal gene regulatory network of type 1 conventional dendritic cells (cDC1) to reprogram cancer cells into professional antigen presenting cells (tumor-APCs). Enforced expression of th...

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Bibliografische gegevens
Gepubliceerd in:Sci Immunol
Hoofdauteurs: Zimmermannova, Olga, Ferreira, Alexandra G., Ascic, Ervin, Santiago, Marta Velasco, Kurochkin, Ilia, Hansen, Morten, Met, Özcan, Caiado, Inês, Shapiro, Ilja E., Michaux, Justine, Humbert, Marion, Soto-Cabrera, Diego, Benonisson, Hreinn, Silvério-Alves, Rita, Gomez-Jimenez, David, Bernardo, Carina, Bauden, Monika, Andersson, Roland, Höglund, Mattias, Miharada, Kenichi, Nakamura, Yukio, Hugues, Stephanie, Greiff, Lennart, Lindstedt, Malin, Rosa, Fábio F., Pires, Cristiana F., Bassani-Sternberg, Michal, Svane, Inge Marie, Pereira, Carlos-Filipe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2023
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614848/
https://ncbi.nlm.nih.gov/pubmed/37418548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.add4817
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