Restoring Tumor Immunogenicity with Dendritic Cell Reprogramming

Decreased antigen presentation contributes to the ability of cancer cells to evade the immune system. We used the minimal gene regulatory network of type 1 conventional dendritic cells (cDC1) to reprogram cancer cells into professional antigen presenting cells (tumor-APCs). Enforced expression of th...

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Vydáno v:Sci Immunol
Hlavní autoři: Zimmermannova, Olga, Ferreira, Alexandra G., Ascic, Ervin, Santiago, Marta Velasco, Kurochkin, Ilia, Hansen, Morten, Met, Özcan, Caiado, Inês, Shapiro, Ilja E., Michaux, Justine, Humbert, Marion, Soto-Cabrera, Diego, Benonisson, Hreinn, Silvério-Alves, Rita, Gomez-Jimenez, David, Bernardo, Carina, Bauden, Monika, Andersson, Roland, Höglund, Mattias, Miharada, Kenichi, Nakamura, Yukio, Hugues, Stephanie, Greiff, Lennart, Lindstedt, Malin, Rosa, Fábio F., Pires, Cristiana F., Bassani-Sternberg, Michal, Svane, Inge Marie, Pereira, Carlos-Filipe
Médium: Artigo
Jazyk:Inglês
Vydáno: 2023
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614848/
https://ncbi.nlm.nih.gov/pubmed/37418548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.add4817
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