Restoring Tumor Immunogenicity with Dendritic Cell Reprogramming

Decreased antigen presentation contributes to the ability of cancer cells to evade the immune system. We used the minimal gene regulatory network of type 1 conventional dendritic cells (cDC1) to reprogram cancer cells into professional antigen presenting cells (tumor-APCs). Enforced expression of th...

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Bibliografiska uppgifter
I publikationen:Sci Immunol
Huvudupphovsmän: Zimmermannova, Olga, Ferreira, Alexandra G., Ascic, Ervin, Santiago, Marta Velasco, Kurochkin, Ilia, Hansen, Morten, Met, Özcan, Caiado, Inês, Shapiro, Ilja E., Michaux, Justine, Humbert, Marion, Soto-Cabrera, Diego, Benonisson, Hreinn, Silvério-Alves, Rita, Gomez-Jimenez, David, Bernardo, Carina, Bauden, Monika, Andersson, Roland, Höglund, Mattias, Miharada, Kenichi, Nakamura, Yukio, Hugues, Stephanie, Greiff, Lennart, Lindstedt, Malin, Rosa, Fábio F., Pires, Cristiana F., Bassani-Sternberg, Michal, Svane, Inge Marie, Pereira, Carlos-Filipe
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2023
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614848/
https://ncbi.nlm.nih.gov/pubmed/37418548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.add4817
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