Restoring Tumor Immunogenicity with Dendritic Cell Reprogramming

Decreased antigen presentation contributes to the ability of cancer cells to evade the immune system. We used the minimal gene regulatory network of type 1 conventional dendritic cells (cDC1) to reprogram cancer cells into professional antigen presenting cells (tumor-APCs). Enforced expression of th...

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Foilsithe in:Sci Immunol
Main Authors: Zimmermannova, Olga, Ferreira, Alexandra G., Ascic, Ervin, Santiago, Marta Velasco, Kurochkin, Ilia, Hansen, Morten, Met, Özcan, Caiado, Inês, Shapiro, Ilja E., Michaux, Justine, Humbert, Marion, Soto-Cabrera, Diego, Benonisson, Hreinn, Silvério-Alves, Rita, Gomez-Jimenez, David, Bernardo, Carina, Bauden, Monika, Andersson, Roland, Höglund, Mattias, Miharada, Kenichi, Nakamura, Yukio, Hugues, Stephanie, Greiff, Lennart, Lindstedt, Malin, Rosa, Fábio F., Pires, Cristiana F., Bassani-Sternberg, Michal, Svane, Inge Marie, Pereira, Carlos-Filipe
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2023
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614848/
https://ncbi.nlm.nih.gov/pubmed/37418548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.add4817
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