Dolutegravir as First- or Second-Line Treatment for HIV-1 Infection in Children

BACKGROUND: Children with human immunodeficiency virus type 1 (HIV-1) infection have limited options for effective antiretroviral treatment (ART). METHODS: We conducted an open-label, randomized, noninferiority trial comparing three-drug ART based on the HIV integrase inhibitor dolutegravir with sta...

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Publicat a:N Engl J Med
Autors principals: Turkova, A., White, E., Mujuru, H.A., Kekitiinwa, A.R., Kityo, C.M., Violari, A., Lugemwa, A., Cressey, T.R., Musoke, P., Variava, E., Cotton, M.F., Archary, M., Puthanakit, T., Behuhuma, O., Kobbe, R., Welch, S.B., Bwakura-Dangarembizi, M., Amuge, P., Kaudha, E., Barlow-Mosha, L., Makumbi, S., Ramsagar, N., Ngampiyaskul, C., Musoro, G., Atwine, L., Liberty, A., Musiime, V., Bbuye, D., Ahimbisibwe, G.M., Chalermpantmetagul, S., Ali, S., Sarfati, T., Wynne, B., Shakeshaft, C., Colbers, A., Klein, N., Bernays, S., Saïdi, Y., Coelho, A., Grossele, T., Compagnucci, A., Giaquinto, C., Rojo, P., Ford, D., Gibb, D.M.
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614690/
https://ncbi.nlm.nih.gov/pubmed/34965338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa2108793
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