Simplified dolutegravir dosing for children with HIV weighing 20 kg or more: pharmacokinetic and safety substudies of the multicentre, randomised ODYSSEY trial

BACKGROUND: Paediatric dolutegravir doses approved by stringent regulatory authorities (SRAs) for children weighing 20 kg to less than 40 kg until recently required 25 mg and 10 mg film-coated tablets. These tablets are not readily available in low-resource settings where the burden of HIV is highes...

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Vydáno v:Lancet HIV
Hlavní autoři: Bollen, Pauline D J, Moore, Cecilia L, Mujuru, Hilda A, Makumbi, Shafic, Kekitiinwa, Adeodata R, Kaudha, Elisabeth, Parker, Anna, Musoro, Godfrey, Nanduudu, Annet, Lugemwa, Abbas, Amuge, Pauline, Hakim, James G, Rojo, Pablo, Giaquinto, Carlo, Colbers, Angela, Gibb, Diana M, Ford, Deborah, Turkova, Anna, Burger, David M
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier B.V 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445428/
https://ncbi.nlm.nih.gov/pubmed/32763217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2352-3018(20)30189-2
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