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Scratching the itch with cryo-EM
Cryo-EM structures of Mas-related G-protein-coupled receptors (MRGPRs) that are involved in the allergic reaction and itch response reveal structural insights into their activation mechanism, and offer the potential to discover new therapeutic agents for pain and hypersensitivity reactions.
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| Vydáno v: | Nat Chem Biol |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2022
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614530/ https://ncbi.nlm.nih.gov/pubmed/35046612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-021-00959-4 |
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