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Scratching the itch with cryo-EM
Cryo-EM structures of Mas-related G-protein-coupled receptors (MRGPRs) that are involved in the allergic reaction and itch response reveal structural insights into their activation mechanism, and offer the potential to discover new therapeutic agents for pain and hypersensitivity reactions.
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| Published in: | Nat Chem Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2022
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614530/ https://ncbi.nlm.nih.gov/pubmed/35046612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-021-00959-4 |
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