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Scratching the itch with cryo-EM

Cryo-EM structures of Mas-related G-protein-coupled receptors (MRGPRs) that are involved in the allergic reaction and itch response reveal structural insights into their activation mechanism, and offer the potential to discover new therapeutic agents for pain and hypersensitivity reactions.

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Chem Biol
Päätekijät: Maharana, Jagannath, Sarma, Parishmita, Shukla, Arun K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2022
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614530/
https://ncbi.nlm.nih.gov/pubmed/35046612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-021-00959-4
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