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T-independent responses to polysaccharides in humans mobilize marginal zone B cells prediversified against gut bacterial antigens
Marginal zone (MZ) B cells are one of the main actors of T-independent (TI) responses in mice. To identify the B cell subset(s) involved in such responses in humans, we vaccinated healthy individuals with Pneumovax, a model TI vaccine. By high-throughput repertoire sequencing of plasma cells (PCs) i...
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| Publicado no: | Sci Immunol |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2023
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614366/ https://ncbi.nlm.nih.gov/pubmed/36706172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.ade1413 |
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