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Splenic marginal zone B cells in humans: where do they mutate their Ig receptor?
Human IgM(+)IgD(+)CD27(+) B cells have mutated Ig genes and harbor a splenic marginal zone phenotype. The group of R. Küppers has studied the expression of the enzyme activation-induced cytidine deaminase (AID) in human spleen samples by immunocytochemistry and failed to detect a significant AID-exp...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Wiley-VCH
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2694967/ https://ncbi.nlm.nih.gov/pubmed/16180256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200535446 |
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